 | 重慶市華雅干細胞技術有限公司 |
15021010459
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GDNF 神經膠質細胞源性的神經營養因子 G-010/050/250
| 參考價 | 面議 |
- 型號 G-010/050/250
- 品牌 StemRD/美國
- 廠商性質 代理商
- 所在地 重慶市
更新時間：2017-01-23 00:01:58瀏覽次數：1030
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產品信息
Glial Cell Line-derived Neurotrophic Factor (GDNF) is a disulfide-linked homodimeric glycoprotein. Itis a neurotrophic factor structurally belonging to the TGF-beta super family. The GDNF precursor encodes a 211 amino acid residue prepro-peptide that is processed pro-teolytically to a dimeric mature protein consisting of two 134 amino acid residue subunits.
StemRD's GDNF is made in human 293 cells which renders natural dimerization and human-specific post-translational modifications. We purified this product through a series of chromatography to near homogeneity.
Purity:
Greater than 95% by SDS-PAGE under reducing conditions and visualized by silver staining.
Biological Activity:
The activity was determined by using a Elk-1 luciferase reporter gene assay in 293 cells cotransfected with cRET receptor (Worby, et al. Glial Cell Line-derived Neurotrophic Factor Signals through the RET Receptor and Activates Mitogen-activated Protein Kinase. J Biol Chem. 1996; 271:23619). The EC50ranges from 1 - 10 ng/ml.
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