tissuegrowth lumegen體外3D血管培養(yǎng)系統(tǒng),血管脈動(dòng)壓力/剪切力加載培養(yǎng)系統(tǒng),Lumegen型號(hào)體外三維血管應(yīng)力加載培養(yǎng)系統(tǒng)(Pulsatile Pressure & Flow Bioreactor) 是一種全新設(shè)計(jì)的血管體外壓應(yīng)力/切應(yīng)力培養(yǎng)裝置,。該系統(tǒng)為體外構(gòu)建的血管提供脈動(dòng)壓應(yīng)力/切應(yīng)力刺激培養(yǎng)環(huán)境，可長(zhǎng)時(shí)間進(jìn)行體外血管壓應(yīng)力/切應(yīng)力刺激三維培養(yǎng)，使血管存活較長(zhǎng)時(shí)間。

電腦軟件控制波形和頻率

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DynaGen® bioreactors provide a controllable, 3D environment for stimulating physiological conditions in vitro. The LumeGen system imparts mechanical
pulsatile pressure to a 3D sample. Applications include investigating cell function, modulating the growth and development of engineered tissues, or acting as a test bed for drug and regenerative medicine technologies.

LumeGen Bioreactor System

Chambers: The LumeGen bioreactor chamber facilitates pulsatile and shear stress stimulation to a single vascular construct. Standard construct sizes may range from
2 - 6mm inner diameter and from 10 to 60mm long.

The modular design allows installation of the scaffold and cell seeding independently of the stimulation system. Multiple ports are available for media access, catheter probe insertion, sample collection, or further customization. This autoclavable chamber has a volume of 60 mL.
Grip Options: LumeGen chambers use a stainless steel barb with an o-ring clamp to immobilize constructs or tissue explants. Standard barb sizes include 2, 3, 4, 5
and 6mm outside diameters and can be interchanged with a universal grip housing.

DynaGen® Stimulator: The LumeGen bioreactor system includes the 6Vr pulsatile pressure mechanical 

stimulator. The 6Vr stimulator features either a 20 or 40
newton linear motor that is lightweight, compact, corrosion
resistant and compatible with most standard incubators.
This stimulator employs pressure control to deliver user
defi ned sine pressure wave forms of physiological
magnitude, with a maximum pressure of 200 mmHg. The
6Vr is integrated with a computer controlled mean fl ow
pump and is capable of low or high-fl ow confi gurations.
Low fl ow confi gurations (0-100ml/min) can accomodate up
to six chambers with a single stimulator. Standard
high-fl ow confi gurations (100 - 800 mL/min) can stimulate
a single chamber. The standard high-fl ow confi guration
can be adapted to accommodate multiple chambers.
Stimulator Specifi cations:
6Vr: Footprint: 6” x 4” x 4” Weight: 4.6 lbs.

GrowthWorks® Control System: A fi fth generation design, the GrowthWorks® Software and Control platform includes advanced capabilities, such as multiple waveform control, data acquisition and multi-motor operation. The intuitive
software runs on a laptop computer under Windows XP and features a simple user interface. User defi ned stimulation profi les are controlled by the software and readily
monitored using graphical displays. Integrated data acquisition routines capture and record data at user prescribed intervals.
Featuring a 32 bit In based CPU and integrated motor
drives, the control hardware communicates with the laptop
using a network cable. GrowthWorks® can be confi gured
to run four stimulators and simultaneously monitor up to 8
transducers, allowing the researcher to customize the
system functionality. The controller can be customized
with additional modules for applications requiring
automation features or additional axes of mechanical
stimulation.